Autornatic Pre-storage Filtration System for Platelet Apheresis
نویسندگان
چکیده
منابع مشابه
Oncogenic and angiogenic growth factors accumulate during routine storage of apheresis platelet concentrates.
PURPOSE Platelet concentrates are important for support of patients with malignancies requiring myelotoxic chemotherapy. During storage, 10% to 15% of platelets may become activated resulting in the release of alpha-granules, which contain growth factors. We hypothesize that, during storage, growth factors accumulate in the plasma, specifically platelet-derived growth factor, vascular endotheli...
متن کاملExploratory studies of extended storage of apheresis platelets in a platelet additive solution (PAS).
To evaluate the poststorage viability of apheresis platelets stored for up to 18 days in 80% platelet additive solution (PAS)/20% plasma, 117 healthy subjects donated platelets using the Haemonetics MCS+, COBE Spectra (Spectra), or Trima Accel (Trima) systems. Control platelets from the same subjects were compared with their stored test PAS platelets by radiolabeling their stored and control pl...
متن کاملPre and post apheresis platelet CD markers evaluation using flow cytometry.
OBJECTIVE To evaluate the effect of apheresis procedure on platelet's activation dependent glycoproteins' expression on their surface. METHODS This study was conducted between June 2012 and June 2014, and comprised blood and platelet samples. Two samples were collected i.e. venous blood sample and apheresed platelet sample from the same donor. Platelet cluster of differentiation markers (41, ...
متن کاملRed cell apheresis with automated in-line filtration.
BACKGROUND The aim of this study was to provide data on concurrent red blood cell (RBC) and platelet (PLT) apheresis with RBC in-line leukoreduction and automated addition of saline-adenine-glucose-mannitol (SAGM) using the new version (V6.0) of Trima Accel®. METHODS In this two-center paired study, each subject completed a test and a control procedure with an interval of 9 weeks between proc...
متن کاملPlatelet Factor 3 Based-clotting Time Assay as a Quality Marker for Long-term Storage of Platelet Concentrates
Background: Platelets rapidly lose their qualities usually after 5 day of storage. Different standard methods have been recommended to check the quality of platelets during storage which some of them show better correlation with other quality markers during storage. The purpose of this study was to demonstrate if platelet factor 3 (PF3) assay could be an indicator of storage lesion and provide ...
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ژورنال
عنوان ژورنال: JAPANES JOURNAL OF MEDICAL INSTRUMENTATION
سال: 1996
ISSN: 0385-440X,1881-4875
DOI: 10.4286/ikakikaigaku.66.9_482